by TdB Labs
Please send an e-mail to email@example.com if you would like to receive a quote, place a bulk order or if you wish to place your order manually.
CAS Number: N/A
Alternative Name: EYD10
Eosin-Y-dextran 10 (EYD10) is a dextran derivative that is labelled with the Eosin Y dye and it is currently produced at a molecular weight of 10kDa.
Eosin-Y-dextran 10 (EYD10) is a dextran-based derivative labeled with the dye Eosin Y (2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl) benzoate; CAS No: 17372-87-1). Dextran is marked using a special technique created by TdB Labs, which enables a significant level of functionalization. The method utilizes the amino groups of a previously functionalized dextran to create a linker that involves amide groups. This linker provides considerable spacing between the substrate and the fluorophore, while also offering H-bonding opportunities (intramolecular and/or intermolecular, e.g., with solvent molecules).
Owing to the presence of Eosin Y, EYD10 exhibits strong orange fluorescence (excitation max. at λ=532 nm and fluorescence max. at λ=555 nm in water). The fluorescence quantum yield for EYD10 sample with a degree of fluorescent labelling of 0.003 mmol EY/g sample has been determined to be Φ=0.38.
Storage and Stability
EYD10 should be stored in a well-sealed container in the dark, at room temperature, and has a shelf-life of 6 years under these conditions.
EYD10 is delivered as a dark ruby red color amorphous powder readily soluble at concentrations close to 100 mg/ml in water and 50 mg/ml in DMSO, where mild heating (up to max 60oC) might be required. However, it is insoluble in methanol and ethanol.
EYD10 is suitable for a range of potential applications such as in cell permeability studies, as a fluorescent nanocarrier for drug delivery applications and research thereof, and as a pH indicator.